Trying to lose a few pounds. Besides the usual recommendations of increasing your exercise and watching what you eat, here comes a new suggestion: Get more sleep. Not getting enough sleep appears to contribute to weight gain by increasing the levels of a natural appetite stimulant. This substance, called 2-AG or 2-arachidonoylglycerol is a component of the endocannabinoid system, which is found throughout the body. This system plays an important role in regulating our enjoyment of eating. 2-AG is a cannabinoid, similar to those in marijuana. So if you want to eliminate the munchies, get some sleep.